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Medical condition/treatment

Spinal muscular atrophy (SMA)

disc prolapse

Muscles and spine

disc prolapse

Spinal muscular atrophy (SMA) is a genetic disorder that causes progressive muscle loss and weakness. It affects the muscles responsible for movement and can cause various difficulties depending on the severity of the disease.

Causes/Description:

Spinal muscular atrophy (SMA) is a genetic disorder that causes progressive muscle weakness and atrophy. SMA is caused by mutations in the SMN1 gene. The exact cause of SMN1 mutations is unknown, but genetics is a significant factor. Other factors may include environmental toxins and neural wiring disorders.

Spinal muscular atrophy (SMA)

disc prolapse

Physiotherapie, Ergotherapie, Atemtherapie, Krankengymnastik, Orthopädietechnik, Ernährungsberatung, Sozialberatung, Hilfsmittelversorgung

disc prolapse

SMA is caused by mutations in certain genes responsible for the function of motor neurons. These mutations lead to a breakdown of motor nerve cells in the spinal cord, leading to muscle weakness and progressive movement problems.

disc prolapse

- Physiotherapy to maintain muscle function - Respiratory therapy to support breathing - Occupational therapy to promote independence - Control of respiratory infections and nutrition

disc prolapse

The first description of the SMA comes from Guido Werdnig in 1891. Friedrich Hoffmann identified SMA as an independent disease in 1956. In 1995, the SMA genes SMN1 and SMN2 were discovered. The first drug to treat SMA (Spinraza) was approved in 2016.

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